Effect of creatine monohydrate loading on serum creatine kinase and downhill running-induced muscle soreness in male mountain climbers

Document Type : Research Paper

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Abstract

Background: Based on the conflict results about the effect of creatine supplement on delayed onset muscle soreness (DOMS), the present study was carried out to determine the effect of creatine monohydrate loading on serum total creatine kinase (CK) and downhill running-induced muscle soreness in male mountaineers.
Methodology: Twenty volunteer healthy male mountain climbers (Aged 20-28 year, Body fat 8-12%, and VO2max 50-55 ml/kg/min) in a randomized and double-blind design were divided into two equal creatine and placebo groups. Each participant received 300 mg/kg/day creatine monohydrate or dextrose for five consecutive days. After supplementation period, all subjects were participated in downhill running protocol with 65% maximum oxygen consumption, -15% on a treadmill for 30 minutes. Blood samples were obtained in the four phases: Before and after loading phase; immediately and 24hours after downhill running protocol. Data were expressed as means ± SD and analyzed by repeated measure ANOVA, Bonferroni and independent samples t tests at P<0.05.
Results: The serum total creatine kinase (CK) and perceived muscle pain were significantly increased in both groups after the downhill running (P<0.05). However, the 24-hour change ranges of serum CK in creatine group were significantly less than in placebo group (P<0.05) while, the 24-hour differences of lower limb’s swelling, flexibility, maximal isometric strength, and explosive power between two groups were not significant (P>0.05).
Conclusion: Based on the present results, it can be concluded that the 5-day creatine monohydrate loading has effect on some undesirable changes of downhill running-induced muscle soreness in male mountain climbers.

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Applied Research in Sport Management
Volume 1, Issue 2 - Serial Number 2
November 2012
Pages 44-37

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History

  • Receive Date: 22 August 2012
  • Revise Date: 22 September 2012
  • Accept Date: 23 October 2012

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